If you were to investigate a rare cancer in Lynchburg, where might you look for data?

An epidemiologist found five cases of “big toe cancer” in the Yukon Territory. Because there were only a few cases, the epidemiologist decided to conduct a matched case-control study to determine whether shoe size larger than 9 is a risk factor for big toe cancer. Cases were individually matched to one control for daily activity, history of athlete’s foot, and history of ingrown toenails. The following data were gathered:

Shoe size > 9

Pair Case Control
1 Yes No
2 No No
3 No Yes
4 Yes Yes
5 No Yes

  1. Compute the proper measure of association.
  2. Interpret your results.
  3. If you were to investigate a rare cancer in Lynchburg, where might you look for data?
  4. What would be necessary legally and ethically to be able to utilize this data set(s)?