How do you think your listeners will respond to your communication? What questions or feelings will they have? 

Audience

Relationship. How closely do you interact with these listeners? What are their roles relative to you? Will you be engaging in vertical, hierarchical communication? Or are you speaking to your peers, or horizontally?
Information. Do your listeners know a lot about the topic you are communicating about? Is there some additional knowledge they need to know before fulfilling your objective?
Attitude. How do you think your listeners will respond to your communication? What questions or feelings will they have?