Hypothesize how Shelby’s lactate threshold test would change with dedicated aerobic training. What changes would occur within skeletal muscle cells to delay the spilling of lactate into the blood


Part IV – Extracellular Fluid and Blood Composition Changes with Skeletal Muscle Cell Activity

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Questions

14. Suppose you are measuring changes in blood composition in real time in an untrained person like Shelby who
is jogging at a moderate pace on a treadmill and you notice that as lactate levels increase in her blood, so do H+ levels. Why is this? Is lactate the original source of these additional H+ ions?
15. Hypothesize how Shelby’s lactate threshold test would change with dedicated aerobic training. What changes
would occur within skeletal muscle cells to delay the spilling of lactate into the blood

16. Skim back through this case study and identify the causes of H+ production and accumulation in the sarcoplasm, extracellular fluid, and blood. Is lactate ever the original source of these ions or just guilty by association? Then, go back to the very
first page of this case study and re-examine your thoughts from Activity 1. Can you generate a more detailed list
of misconceptions now?
17. What is the relationship between the production of lactate and the burning sensation many people like Shelby
describe after they begin a new exercise regime or activity? How is the brain made “aware” of this situation?
18. Hypothesize what changes could occur within skeletal muscle cells that would help prevent the burning sensation
after completing an aerobic exercise activity like jogging