What is antimicrobial resistance, why it is a problem for humans and animal health

Antimicrobial Resistance. Using logistic regression (in RStudios) to investigate variation in the trends for E.coli resistance (to three major antibiotic classes) in European countries

What is antimicrobial resistance, why it is a problem for humans and animal health (one health). Why E.coli was chosen (as it a hugley common zoonotic pathogen), why resistance to all 3 antimicrobials is being looked at.