Which amino acids of the protein are involved? What triggers the interaction?

MYOSIN-ACTIN PROTEIN LIGAND INTERACTION Suggested report structure The overall structure of the report should be organised to present the information on myosin-actin protein-lig and interaction in a clear, logical fashion. Introduction (first paragraph)

• Describe the two components of the protein-ligand pair• Describe where this interaction occurs (i.e. in which species, cell type or organ the proteinand ligand interact)

• Describe the primary biological function that the interaction mediates (i.e. part of immuneresponses, cell signalling, metabolism, etc) Second section•

Describe the interaction in greater molecular detail, try to include details such as:

Which amino acids of the protein are involved? What triggers the interaction?

Does the interaction change the confirmation/structure of the protein and /or ligand?

Are there cofactors required for this interaction or inhibitors that can block it?Third section

•Other relevant or interesting information related to the interaction not

•Can the interaction be artificially manipulated or utilised for another purpose?(likeantibody usage in biotechnology)o

Does this interaction vary in different cells or organisms?

Do mutations that affect the expression protein cause genetic disease?(if so how?)

Conclusion

• Briefly summarise the major points covered in the report, emphasising the importance or key features of the protein-ligand interacti